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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
M4692-32N.100 | 100 µg | - | - |
3 - 19 business days* |
629.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
MSH2 is a member of the highly conserved families of postreplication mismatch repair genes, MutS... more
Product information "Anti-MSH2 (MutS Homolog 2, MutS Homolog 2 Colon Cancer Nonpolyposis Type 1, MutS Protein Homolog 2,"
MSH2 is a member of the highly conserved families of postreplication mismatch repair genes, MutS and MaiL, involved in increasing the fidelity of replication by specific repair of DNA polymerase misincorporation errors. It is the human homolog of the bacterial MutS and S. cerevisiae MSH proteins. It maps to human chromosome 2p22-21 near a locus implicated in hereditary nonpolyposis colon cancer (HNPCC) and thus is the HNPCC gene. Defects in MSH2 accounts for most cases of sporadic colorectal tumors. Due to other functions besides its role in DNA repair, that include regulation of cell proliferation and apoptosis, it has recently been shown to be of importance for pathogenesis and progression of cancer. It is ubiquitously expressed. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1-3ug/ml, Optimal dilutions to be determined by the researcher. Positive Control: HCT-116 cell lysate, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: | United States Biological |
Supplier-Nr: | M4692-32N |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | Synthetic peptide corresponding to aa550-600 of human MSH2. |
Format: | Affinity Purified |
Database Information
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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