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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
G-IVMB0181.1 | 1 mg | - | - |
9 - 20 business days* |
440.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Functional grade preclinical antibodies are manufactured in an animal free facility using only In... more
Product information "Anti-Mouse/Rat CD126 (IL-6Ralpha) In Vivo Antibody - Low Endotoxin"
Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Endotoxin level: < 1.0 EU/mg as determined by the LAL method. Concentration: > 5.0 mg/ml. Storage and Handling: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. Protein function: Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation leads to the regulation of the immune response, acute-phase reactions and hematopoiesis. The interaction with membrane-bound IL6R and IL6ST stimulates 'classic signaling', the restricted expression of the IL6R limits classic IL6 signaling to only a few tissues such as the liver and some cells of the immune system. Whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells. [The UniProt Consortium]
Keywords: | Anti-Il6r |
Supplier: | Assay Genie |
Supplier-Nr: | IVMB0181 |
Properties
Application: | FA, FC, N, WB |
Antibody Type: | Monoclonal |
Clone: | D7715A7 (15A7) |
Conjugate: | No |
Host: | Rat |
Species reactivity: | mouse |
Database Information
KEGG ID : | K05055 | Matching products |
UniProt ID : | P22272 | Matching products |
Handling & Safety
Storage: | +4°C (-70 °C for long term storage) |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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