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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-AB-F1116B.25 | 25 µg | - |
7 - 16 business days* |
55.00€
|
|||
E-AB-F1116B.100 | 100 µg | - |
7 - 16 business days* |
158.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin alpha chain also... more
Product information "Anti-Mouse CD49b, Biotin conjugated, clone DX5"
DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin alpha chain also known as alpha2 integrin, VLA-2 alpha chain, and integrin alpha2 chain. CD49b non-covalently associates with CD29 (beta1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen. Protein function: Integrin alpha-2/beta-1 is a collagen receptor, being responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. It is also a receptor for laminins, collagen C-propeptides and E- cadherin. Mice homozygous for a null mutation in the alpha-2 die very early in embryogenesis. [The UniProt Consortium]
Keywords: | Anti-GPIa, Anti-Itga2, Anti-CD49b, Anti-Integrin alpha-2, Anti-Collagen receptor, Anti-VLA-2 subunit alpha, Anti-Platelet membrane glycoprotein Ia, Anti-CD49 antigen-like family member B, Biotin Anti-Mouse CD49b Antibody[DX5] |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-F1116B |
Properties
Application: | FC, FC (membrane) |
Antibody Type: | Monoclonal |
Clone: | DX5 |
Conjugate: | Biotin |
Host: | Rat |
Species reactivity: | mouse |
Database Information
KEGG ID : | K06481 | Matching products |
UniProt ID : | Q62469 | Matching products |
Gene ID | GeneID 16398 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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