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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-12-1211-100 | 100 µg | - |
3 - 11 business days* |
850.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the... more
Product information "Anti-MMP3 Recombinant Mouse Monoclonal Antibody (clone:rMMP3/1730)"
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies. Protein function: Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V, collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase. [The UniProt Consortium]
Keywords: | Anti-SL-1, Anti-MMP3, Anti-STMY1, Anti-MMP-3, Anti-Transin-1, EC=3.4.24.17, Anti-Stromelysin-1, Anti-Matrix metalloproteinase-3, Anti-MMP3 Recombinant Mouse Monoclonal Antibody (Clone:rMMP3/1730) |
Supplier: | Abeomics |
Supplier-Nr: | 12-1211 |
Properties
Application: | IHC |
Antibody Type: | Monoclonal |
Clone: | rMMP3/1730 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Recombinant fragment of human MMP3 (around aa 317-327) (exact sequence is proprietary) |
Format: | Purified |
Database Information
KEGG ID : | K01394 | Matching products |
UniProt ID : | P08254 | Matching products |
Gene ID | GeneID 4314 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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