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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| G-CAB15690.50 | 50 µl | - | - |
9 - 20 business days* |
352.00€
|
||
| G-CAB15690.100 | 100 µl | - |
9 - 20 business days* |
448.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
WB 1:500 - 1:2000. Protein function: Chromatin reader component of the super elongation complex... more
Product information "Anti-MLLT3"
WB 1:500 - 1:2000. Protein function: Chromatin reader component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA (PubMed:20159561, PubMed:20471948, PubMed:25417107, PubMed:27105114, PubMed:27545619). Specifically recognizes and binds acylated histone H3, with a marked preference for histone H3 that is crotonylated (PubMed:25417107, PubMed:27105114, PubMed:27545619). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors (PubMed:25417107, PubMed:27105114, PubMed:27545619). Recognizes and binds histone H3 crotonylated at 'Lys-9' (H3K9cr), and with slightly lower affinity histone H3 crotonylated at 'Lys-18' (H3K18cr) (PubMed:27105114). Also recognizes and binds histone H3 acetylated at 'Lys-9' (H3K9ac), but with lower affinity than crotonylated histone H3 (PubMed:25417107, PubMed:27105114). In the SEC complex, MLLT3 is required to recruit the complex to crotonylated histones (PubMed:27105114, PubMed:27545619). [The UniProt Consortium]
| Keywords: | Anti-AF9, Anti-Protein AF-9, Anti-YEATS domain-containing protein 3, Anti-ALL1-fused gene from chromosome 9 protein, Anti-Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein, MLLT3 Polyclonal Antibody (CAB15690) |
| Supplier: | Assay Genie |
| Supplier-Nr: | CAB15690 |
Properties
| Application: | WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
Database Information
| KEGG ID : | K15187 | Matching products |
| UniProt ID : | P42568 | Matching products |
| Gene ID | GeneID 4300 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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