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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES2791.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES2791.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family.... more
Product information "Anti-MINK1"
This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. [provided by RefSeq, Mar 2016], Protein function: Serine/threonine kinase which acts as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. Required for normal synaptic density, dendrite complexity, as well as surface AMPA receptor expression in hippocampal neurons. Can activate the JNK and MAPK14/p38 pathways and mediates stimulation of the stress-activated protein kinase MAPK14/p38 MAPK downstream of the Raf/ERK pathway. Phosphorylates: TANC1 upon stimulation by RAP2A, MBP and SMAD1. Has an essential function in negative selection of thymocytes, perhaps by coupling NCK1 to activation of JNK1. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.. Cellular localization: Cytoplasm . Cell junction, synapse, postsynaptic density . Cell projection, axon . Cell projection, dendrite ., [Isoform 4]: Golgi apparatus.
Keywords: | Anti-MEKKK 6, EC=2.7.11.1, Anti-MEK kinase kinase 6, Anti-GCK family kinase MiNK, Anti-Misshapen-like kinase 1, Anti-Misshapen/NIK-related kinase, Anti-MAPK/ERK kinase kinase kinase 6, Anti-Mitogen-activated protein kinase kinase kinase kinase 6, MINK1 ra |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES2791 |
Properties
Application: | WB, IHC, IF, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | The antiserum was produced against synthesized peptide derived from human MAP4K6. AA range:401-450 |
MW: | 150 kD |
Format: | Antiserum |
Database Information
KEGG ID : | K04413 | Matching products |
UniProt ID : | Q8N4C8 | Matching products |
Gene ID | GeneID 50488 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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