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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ARG65244.100 | 100 µg | - | - |
6 - 14 business days* |
784.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Involved in transcriptional regulation. Binds to HOX or PBX proteins to form... more
Product information "Anti-MEIS2, Internal"
Protein function: Involved in transcriptional regulation. Binds to HOX or PBX proteins to form dimers, or to a DNA-bound dimer of PBX and HOX proteins and thought to have a role in stabilization of the homeoprotein-DNA complex. Isoform 3/Meis2B is required for the activity of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells involved in the transcriptional activation of the ELA1 enhancer, the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element, MEIS2 is not involved in complex DNA-binding. Probably in complex with PBX1, is involved in transcriptional regulation by KLF4. Isoform 3/Meis2B and isoform 4/Meis2D can bind to a EPHA8 promoter sequence containing the DNA motif 5'-CGGTCA-3', in cooperation with a PBX protein (such as PBX2) is proposed to be involved in the transcriptional activation of EPHA8 in the developing midbrain. May be involved in regulation of myeloid differentiation. Can bind to the DNA sequence 5'-TGACAG-3'in the activator ACT sequence of the D(1A) dopamine receptor (DRD1) promoter and activate DRD1 transcription, isoform 5/Meis2E cannot activate DRD1 transcription. [The UniProt Consortium]
Keywords: | Anti-MRG1, Anti-MEIS2, Anti-Homeobox protein Meis2, Anti-Meis1-related protein 1 |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG65244 |
Properties
Application: | ELISA, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Goat |
Species reactivity: | mouse, rat (Expected: human, canine, bovine) |
Immunogen: | C-QSNRAGFLLDPSVSQ |
Format: | Ammonium Sulfate Precipitated |
Database Information
KEGG ID : | K16670 | Matching products |
UniProt ID : | O14770 | Matching products |
Gene ID | GeneID 4212 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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