Anti-MATR3

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-65521.60 60 µl -

7 - 16 business days*

198.00€
E-AB-65521.120 120 µl -

7 - 16 business days*

317.00€
E-AB-65521.200 200 µl -

7 - 16 business days*

525.00€
 
This gene encodes a nuclear matrix protein, which is proposed to stabilize certain messenger RNA... more
Product information "Anti-MATR3"
This gene encodes a nuclear matrix protein, which is proposed to stabilize certain messenger RNA species. Mutations of this gene are associated with distal myopathy 2, which often includes vocal cord and pharyngeal weakness. Alternatively spliced transcript variants, including read-through transcripts composed of the upstream small nucleolar RNA host gene 4 (non-protein coding) and matrin 3 gene sequence, have been identified. Pseudogenes of this gene are located on chromosomes 1 and X. Protein function: May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway (PubMed:28712728). May bind to specific miRNA hairpins (PubMed:28431233). [The UniProt Consortium]
Keywords: Anti-MATR3, Anti-KIAA0723, Anti-Matrin-3, MATR3 Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-65521

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Recombinant protein of human MATR3

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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