Anti-MAPKAP1 (Mitogen-activated Protein Kinase Associated Protein 1, MEKK2 Interacting Protein 1, MI

Mip1 is a novel member of a group of highly conserved proteins. Originally identified as a RAS suppressor protein, Mip1 is a human ortholog of S. cerevisiae Sin1. Studies reveal that Mip1 interacts with proteins involved in MAPK signaling including MEKK2 and participates in the regulation of MEKK2 activation and signaling. It also has been found to bind to JNK and might act as a scaffold molecule in the regulation of JNK signaling. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-2ug/ml, Optimal dilutions to be determined by the researcher. Positive Control: Human heart or skeletal muscle cell lysate, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.