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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ARG66695.100 | 100 µg | - | - |
6 - 14 business days* |
584.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Plays a role in various cellular processes such as proliferation,... more
Product information "Anti-MAPK7 / ERK5"
Protein function: Plays a role in various cellular processes such as proliferation, differentiation and cell survival. The upstream activator of MAPK7 is the MAPK kinase MAP2K5. Upon activation, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C. EGF activates MAPK7 through a Ras-independent and MAP2K5-dependent pathway. May have a role in muscle cell differentiation. May be important for endothelial function and maintenance of blood vessel integrity. MAP2K5 and MAPK7 interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. Phosphorylates SGK1 at Ser-78 and this is required for growth factor-induced cell cycle progression. Involved in the regulation of p53/TP53 by disrupting the PML-MDM2 interaction. [The UniProt Consortium]
Keywords: | Anti-BMK1, Anti-MAPK7, Anti-ERK-5, Anti-BMK-1, Anti-MAPK 7, EC=2.7.11.24, Anti-MAP kinase 7, Anti-Big MAP kinase 1, Anti-Mitogen-activated protein kinase 7, Anti-Extracellular signal-regulated kinase 5 |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG66695 |
Properties
Application: | IHC (paraffin), WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Recombinant protein of Human MAPK7 / ERK5 |
MW: | 88 kD |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K04464 | Matching products |
UniProt ID : | Q13164 | Matching products |
Gene ID | GeneID 5598 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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