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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A302-143A-T | 10 µl (2 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A302-143A | 100 µl | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Plays a significant role in regulating cell proliferation, survival and death... more
Product information "Anti-MADD"
Protein function: Plays a significant role in regulating cell proliferation, survival and death through alternative mRNA splicing. Isoform 5 shows increased cell proliferation and isoform 2 shows decreased. Converts GDP-bound inactive form of RAB3A, RAB3C and RAB3D to the GTP-bound active forms. Component of the TNFRSF1A signaling complex: MADD links TNFRSF1A with MAP kinase activation. Plays an important regulatory role in physiological cell death (TNF-alpha-induced, caspase-mediated apoptosis), isoform 1 is susceptible to inducing apoptosis, isoform 5 is resistant and isoform 3 and isoform 4 have no effect. [The UniProt Consortium]
Keywords: | Anti-Rab3 GDP/GTP exchange factor, Anti-Insulinoma glucagonoma clone 20, Anti-MAP kinase-activating death domain protein, Anti-Differentially expressed in normal and neoplastic cells |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A302-143A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: rat, dog, rabbit, panda, orangutan, rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, crab-eating macaque, small-eared galago, northern white-cheeked gibbon) |
Immunogen: | synthetic peptide. The epitope recognized by A302-143A-T maps to a region between residue 1100 and 1150 of human MAP-kinase activating death domain using the numbering given in entry NP_003673.3 (GeneID 8567). |
Format: | Antigen Affinity Purified |
Database Information
UniProt ID : | Q8WXG6 | Matching products |
Gene ID | GeneID 8567 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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