Anti-MADD

Item number Size Datasheet Manual SDS Delivery time Quantity Price
200-401-CP6 100 µg - -

6 - 10 business days*

684.00€
 
Anti-MADD Antibody is purified by DEAE purification methods. Cross reactivity with MADD from... more
Product information "Anti-MADD"
Anti-MADD Antibody is purified by DEAE purification methods. Cross reactivity with MADD from other sources has not been determined. Protein function: Plays a significant role in regulating cell proliferation, survival and death through alternative mRNA splicing. Isoform 5 shows increased cell proliferation and isoform 2 shows decreased. Converts GDP-bound inactive form of RAB3A, RAB3C and RAB3D to the GTP-bound active forms. Component of the TNFRSF1A signaling complex: MADD links TNFRSF1A with MAP kinase activation. Plays an important regulatory role in physiological cell death (TNF-alpha-induced, caspase-mediated apoptosis), isoform 1 is susceptible to inducing apoptosis, isoform 5 is resistant and isoform 3 and isoform 4 have no effect. [The UniProt Consortium]
Keywords: Anti-Rab3 GDP/GTP exchange factor, Anti-Insulinoma glucagonoma clone 20, Anti-MAP kinase-activating death domain protein, Anti-Differentially expressed in normal and neoplastic cells
Supplier: Rockland Immunochemicals
Supplier-Nr: 200-401-CP6

Properties

Application: ELISA, IFM, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Peptide corresponding to amino acids near the C-terminus of human MADD.
Format: Purified

Database Information

UniProt ID : Q8WXG6 | Matching products
Gene ID GeneID 8567 | Matching products

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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