Anti-MACF1

Anti-MACF1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A304-564A-T 10 µl (10 µg) -

2 - 8 business days*

164.00€
A304-564A 100 µl (100 µg) -

2 - 8 business days*

588.00€
 
Protein function: Isoform 2 is a F-actin-binding protein which may play a role in cross-linking... more
Product information "Anti-MACF1"
Protein function: Isoform 2 is a F-actin-binding protein which may play a role in cross-linking actin to other cytoskeletal proteins and also binds to microtubules. Plays an important role in ERBB2- dependent stabilization of microtubules at the cell cortex. Acts as a positive regulator of Wnt receptor signaling pathway and is involved in the translocation of AXIN1 and its associated complex (composed of APC, CTNNB1 and GSK3B) from the cytoplasm to the cell membrane. Has actin-regulated ATPase activity and is essential for controlling focal adhesions (FAs) assembly and dynamics. May play role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with GOLGA4. Plays a key role in wound healing and epidermal cell migration. Required for efficient upward migration of bulge cells in response to wounding and this function is primarily rooted in its ability to coordinate MT dynamics and polarize hair follicle stem cells. [The UniProt Consortium]
Keywords: Anti-MACF1, Anti-ABP620, Anti-Macrophin-1, Anti-Trabeculin-alpha, Anti-620 kDa actin-binding protein, Anti-Actin cross-linking family protein 7, Anti-Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5
Supplier: Bethyl Laboratories
Supplier-Nr: A304-564A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse (Expected: rat, sheep, bovine, dog, horse, rabbit, pig, orangutan, rhesus monkey, cetartiodactyla, white-tufted-ear marmoset, cat, african elephant, gray short-tailed opossum, european domestic ferret, brandt's bat, chinese tree shrew)
Immunogen: synthetic peptide. The epitope recognized by A304-564A-T maps to a region between residue 1975 to 2025 of human Microtubule-Actin Crosslinking Factor 1 using the numbering given in entry NP_036222.3 (GeneID 23499).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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