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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES2729.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES2729.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to... more
Product information "Anti-LT-beta"
Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008], Protein function: Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface. Isoform 2 is probably non-functional. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.. Cellular localization: Membrane , Single-pass type II membrane protein .
Keywords: | Anti-LTB, Anti-TNFC, Anti-TNF-C, Anti-LT-beta, Anti-Lymphotoxin-beta, Anti-Tumor necrosis factor C, Anti-Tumor necrosis factor ligand superfamily member 3, LT-beta rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES2729 |
Properties
Application: | WB, IF, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | The antiserum was produced against synthesized peptide derived from human TNFC. AA range:181-230 |
MW: | 22 kD |
Format: | Antiserum |
Database Information
KEGG ID : | K03157 | Matching products |
UniProt ID : | Q06643 | Matching products |
Gene ID | GeneID 4050 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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