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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-30-1366-0.1 | 100 µg | - |
3 - 11 business days* |
653.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
LST1 (leukocyte-specific transcript, also known as B144) is expressed in cells of... more
Product information "Anti-LST1 Monoclonal Antibody (Clone:LST1/02)"
LST1 (leukocyte-specific transcript, also known as B144) is expressed in cells of myeloid/erythroid lineage (monocytes, granulocytes, dendritic cells, platelets, erythrocytes). At least 14 alternatively spliced variants (LST1/A - LST1/N) can be detected, some of them (LST1/A, B, C, G, I, K) are transmembrane cell surface-exposed forms, the other are soluble. LST1 induces production of long, thin filopodia in dendritic cells, has an inhibitory effect on lymphocyte proliferation and may have an immunomodulatory role. LST1/A is an 11 kDa transmembrane adaptor present in membrane rafts and forms spontaneously covalent homodimers. Its intracellular domain contains two tyrosine motifs, one of them being an ITIM very similar to such motifs in Siglec. Protein function: Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation. [The UniProt Consortium]
Keywords: | Anti-LST1, Anti-B144, Anti-Protein B144, Anti-Leukocyte-specific transcript 1 protein, Anti-LST1 Monoclonal Antibody (Clone:LST1/02) |
Supplier: | Abeomics |
Supplier-Nr: | 30-1366 |
Properties
Application: | IP, WB, ICC |
Antibody Type: | Monoclonal |
Clone: | LST1/02 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | KLH-fused peptide corresponding to amino acids SSEGPDLRGRDKRGT of human LST1 |
Format: | Affinity Purified |
Database Information
UniProt ID : | O00453 | Matching products |
Gene ID | GeneID 7940 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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