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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
200-306-W60 | 100 µg | - | - |
6 - 10 business days* |
713.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Anti-LRRK2/Dardarin Antibody was purified from concentrated tissue culture supernate by Protein G... more
Product information "Anti-LRRK2/Dardarin, clone S138-6, Biotin Conjugated"
Anti-LRRK2/Dardarin Antibody was purified from concentrated tissue culture supernate by Protein G chromatography. BLAST analysis suggests 83% similarity to mouse, 83% similarity to rat and no similarity to LRRK1. Protein function: Positively regulates autophagy through a calcium- dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). Plays a role in synaptic vesicle trafficking. Phosphorylates PRDX3. Has GTPase activity. May play a role in the phosphorylation of proteins central to Parkinson disease. [The UniProt Consortium]
Keywords: | Anti-LRRK2, Anti-PARK8, Anti-Dardarin, EC=2.7.11.1, Anti-Leucine-rich repeat serine/threonine-protein kinase 2 |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 200-306-W60 |
Properties
Application: | ELISA, WB |
Antibody Type: | Monoclonal |
Clone: | S138-6 |
Conjugate: | Biotin |
Host: | Mouse |
Species reactivity: | human, rat, mouse |
Immunogen: | Fusion protein containing amino acids 1-500 of human LRRK2. |
Format: | Purified |
Database Information
KEGG ID : | K08844 | Matching products |
UniProt ID : | Q5S007 | Matching products |
Gene ID | GeneID 120892 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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