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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES6686.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES6686.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This gene encodes a member of the lysophospholipid acyltransferase family. The encoded enzyme may... more
Product information "Anti-LPCAT2"
This gene encodes a member of the lysophospholipid acyltransferase family. The encoded enzyme may function in two ways: to catalyze the biosynthesis of platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) from 1-O-alkyl-sn-glycero-3-phosphocholine, and to catalyze the synthesis of glycerophospholipid precursors from arachidonyl-CoA and lysophosphatidylcholine. The encoded protein may function in membrane biogenesis and production of platelet-activating factor in inflammatory cells. The enzyme may localize to the endoplasmic reticulum and the Golgi. [provided by RefSeq, Feb 2009], Protein function: Exhibits both acyltransferase and acetyltransferase activities (PubMed:17182612, PubMed:20363836, PubMed:21498505). Catalyzes the conversion of lysophosphatidylcholine (1-acyl-sn-glycero- 3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn- glycero-3-phosphocholine or PC) (PubMed:21498505). Catalyzes the conversion 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (PubMed:20363836). Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2- acetyl-sn-glycero-3-phosphocholine (PAF) (PubMed:17182612). Also converts lyso-PAF to 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine (PC), a major component of cell membranes and a PAF precursor. Under resting conditions, acyltransferase activity is preferred. Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases. Involved in the regulation of lipid droplet number and size (PubMed:25491198). [The UniProt Consortium] Recommended dilutions: WB 1:500-2000,IHC-p 1:50-300. Cellular localization: Endoplasmic reticulum membrane , Single-pass type II membrane protein . Golgi apparatus membrane , Single-pass type II membrane protein . Cell membrane , Single-pass type II membrane protein . Lipid droplet .
Keywords: | Anti-LPCAT2, Anti-LPCAT-2, Anti-AGPAT11, Anti-LysoPAFAT, Anti-1-AGPAT 11, Anti-LPAAT-alpha, Anti-LPC acyltransferase 2, Anti-Acyltransferase-like 1, Anti-LysoPC acyltransferase 2, Anti-1-AGP acyltransferase 11, Anti-Lyso-PAF acetyltransferase, LPCAT2 rabb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES6686 |
Properties
Application: | WB, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | The antiserum was produced against synthesized peptide derived from human LPCAT2. AA range:321-370 |
MW: | 50 kD |
Format: | Antiserum |
Database Information
KEGG ID : | K13510 | Matching products |
UniProt ID : | Q7L5N7 | Matching products |
Gene ID | GeneID 54947 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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