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Anti-LMBL3

ELK Biotechnology
Anti-LMBL3
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES19634.50 50 µl - -

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169.00€
ELK-ES19634.100 100 µl - -

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283.00€
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Description Product Citations Certificate of Analysis Reviews 0
Description
Protein function: Is a negative regulator of Notch target genes expression, required for... more
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Product information "Anti-LMBL3"
Protein function: Is a negative regulator of Notch target genes expression, required for RBPJ-mediated transcriptional repression (PubMed:29030483). It recruits KDM1A to Notch-responsive elements and promotes KDM1A-mediated H3K4me demethylation (PubMed:29030483). Involved in the regulation of ubiquitin-dependent degradation of a set of methylated non-histone proteins, including SOX2, DNMT1 and E2F1. It acts as an adapter recruiting the CRL4-DCAF5 E3 ubiquitin ligase complex to methylated target proteins (PubMed:30442713, PubMed:29691401). Required for normal maturation of myeloid progenitor cells. [The UniProt Consortium] Recommended dilutions: WB 1:1000-2000. Cellular localization: Nucleus .
Keywords: Anti-MBT-1, Anti-KIAA1798, Anti-L3mbt-like 3, Anti-L(3)mbt-like protein 3, Anti-H-l(3)mbt-like protein 3, Anti-Lethal(3)malignant brain tumor-like protein 3, LMBL3 rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES19634

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: Synthesized peptide derived from human LMBL3 AA range: 128-178
Format: Purified

Database Information

KEGG ID : K24387 | Matching products
UniProt ID : Q96JM7 | Matching products
Gene ID GeneID 84456 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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