Anti-LIMD1

Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-CAB17585.50 50 µl - -

9 - 20 business days*

352.00€
G-CAB17585.100 100 µl -

9 - 20 business days*

448.00€
 
Protein function: Adapter or scaffold protein which participates in the assembly of numerous... more
Product information "Anti-LIMD1"
Protein function: Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA)-mediated gene silencing and is essential for P-body formation and integrity. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. Acts as a transcriptional corepressor for SNAI1- and SNAI2/SLUG-dependent repression of E-cadherin transcription. Negatively regulates the Hippo signaling pathway and antagonizes phosphorylation of YAP1. Inhibits E2F-mediated transcription, and suppresses the expression of the majority of genes with E2F1-responsive elements. Regulates osteoblast development, function, differentiation and stress osteoclastogenesis. Enhances the ability of TRAF6 to activate adapter protein complex 1 (AP-1) and negatively regulates the canonical Wnt receptor signaling pathway in osteoblasts. May act as a tumor suppressor by inhibiting cell proliferation. [The UniProt Consortium]
Keywords: Anti-LIMD1, Anti-LIM domain-containing protein 1, LIMD1 Rabbit pAb
Supplier: Assay Genie
Supplier-Nr: CAB17585

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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