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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
600-401-CH3 | 100 µg | - | - |
6 - 10 business days* |
684.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Anti-LAMTOR1 antibody was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-LAMTOR1"
Anti-LAMTOR1 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. LAMTOR1 antibody is human, mouse and rat specific. LAMTOR1 antibody is predicted to not cross-react with other LAMTOR family proteins. Protein function: As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. LAMTOR1 is directly responsible for anchoring the Ragulator complex to membranes. Also required for late endosomes/lysosomes biogenesis it may regulate both the recycling of receptors through endosomes and the MAPK signaling pathway through recruitment of some of its components to late endosomes. May be involved in cholesterol homeostasis regulating LDL uptake and cholesterol release from late endosomes/lysosomes. May also play a role in RHOA activation. [The UniProt Consortium]
Keywords: | Anti-PP7157, Anti-LAMTOR1, Anti-C11orf59, Anti-p27RF-Rho, Anti-Lipid raft adaptor protein p18, Anti-Ragulator complex protein LAMTOR1, Anti-p27Kip1-releasing factor from RhoA, Anti-Protein associated with DRMs and endosomes, Anti-Late endosomal/lysosomal |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 600-401-CH3 |
Properties
Application: | ELISA, IHC, IFM, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | 17 amino acid peptide near the N-terminus of human LAMTOR1 |
Format: | Purified |
Database Information
KEGG ID : | K20397 | Matching products |
UniProt ID : | Q6IAA8 | Matching products |
Gene ID | GeneID 55004 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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