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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
029527.100 | 100 µg | - | - |
3 - 19 business days* |
848.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Lysosyme-associated membrane proteins (LAMP) are transmembrane lysosomal glycoproteins, which... more
Product information "Anti-LAMP3 (Lysosome-associated Membrane Glycoprotein 3, LAMP-3, Lysosomal-associated Membrane Prote"
Lysosyme-associated membrane proteins (LAMP) are transmembrane lysosomal glycoproteins, which share a common Gly-Tyr motif as a lysosomal targeting signal. While LAMP-1 and LAMP-2 contain type 1 transmembrane domains, LAMP-3 contains a transmembrane 4 superfamily domain, tetraspanin. FceRI-mediated stimulation of basophils causes LAMP-3 to be translocated from its intracellular localization to the plasma membrane. LAMP-3 thereby serves as a reliable marker for basophil activation. LAMP-3 expression is known to be reported in human bone marrow mast cells and in leukemic human mast cell line (HMC-1), among other cell lines. LAMP3 is shown to be regulated by hypoxia in a panel of tumor cells, via the unfolded protein response (UPR). UPR is a mechanism of adaptation to endoplasmic reticulum stress and is demonstrated to contribute to hypoxic adaptation in tumors through multiple mechanisms. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1ug/ml , Immunohistochemistry (Paraffin): 1:200 Requires HIER using sodium citrate buffer, pH 6.0., Optimal dilutions to be determined by the researcher. Positive Control: MCF-7 cell lysate, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-CD208, Anti-LAMP3, Anti-DCLAMP, Anti-LAMP-3, Anti-DC LAMP, Anti-Protein TSC403, Anti-Lysosomal-associated membrane protein 3, Anti-Lysosome-associated membrane glycoprotein 3, Anti-DC-lysosome-associated membrane glycoprotein |
Supplier: | United States Biological |
Supplier-Nr: | 029527 |
Properties
Application: | IHC, WB |
Antibody Type: | Monoclonal |
Clone: | 13A205 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Format: | Affinity Purified |
Database Information
KEGG ID : | K06562 | Matching products |
UniProt ID : | Q9UQV4 | Matching products |
Gene ID | GeneID 27074 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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