Anti-L1TD1 / ECAT11, clone L1TD1/7941

1 mg/ml in 1X PBS, BSA free, sodium azide free. L1TD1 (LINE-1 type transposase domain containing 1), also known as ECAT11 (ES cell-associated protein 11), is an 865 amino acid protein that belongs to the transposase 22 family and is encoded by a gene that maps to human chromosome 1p31.3. Chromosome 1 spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.