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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ARG63601.100 | 100 µg | - | - |
6 - 14 business days* |
784.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Transcription regulator of erythrocyte development that probably serves as a... more
Product information "Anti-KLF1, N-terminal"
Protein function: Transcription regulator of erythrocyte development that probably serves as a general switch factor during erythropoiesis. Is a dual regulator of fetal-to-adult globin switching. Binds to the CACCC box in the beta-globin gene promoter and acts as a preferential activator of this gene. Furthermore, it binds to the BCL11A promoter and activates expression of BCL11A, which in turn represses the HBG1 and HBG2 genes. This dual activity ensures that, in most adults, fetal hemoglobin levels are low. Able to activate CD44 and AQP1 promoters. When sumoylated, acts as a transcriptional repressor by promoting interaction with CDH2/MI2beta and also represses megakaryocytic differentiation. [The UniProt Consortium]
Keywords: | Anti-KLF1, Anti-EKLF, Anti-Krueppel-like factor 1, Anti-Erythroid krueppel-like transcription factor |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG63601 |
Properties
Application: | ChIP, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Goat |
Species reactivity: | human, mouse (Expected: bovine, canine, swine) |
Immunogen: | ATAETALPSISTLT-C |
Format: | Ammonium Sulfate Precipitated |
Database Information
KEGG ID : | K09204 | Matching products |
UniProt ID : | Q13351 | Matching products |
Gene ID | GeneID 10661 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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