Anti-KCNN4 / KCa3.1 / SKCa4

Anti-KCNN4 / KCa3.1 / SKCa4
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-RQ7087 100 µg - -

3 - 10 business days*

755.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Intermediate conductance calcium-activated... more
Product information "Anti-KCNN4 / KCa3.1 / SKCa4"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Intermediate conductance calcium-activated potassium channel protein 1 (KCNN4, Kca3.1) is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. KCNN4 may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily. Protein function: Forms a voltage-independent potassium channel that is activated by intracellular calcium (PubMed:26148990). Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells (PubMed:17157250, PubMed:18796614). Plays a role in the late stages of EGF-induced macropinocytosis (PubMed:24591580). [The UniProt Consortium]
Keywords: Anti-IK1, Anti-SK4, Anti-KCa4, Anti-KCNN4, Anti-IKCa1, Anti-SKCa4, Anti-SKCa 4, Anti-KCa3.1, Anti-Putative Gardos channel, Anti-Intermediate conductance calcium-activated potassium channel protein 4, KCNN4 Antibody / KCa3.1 / SKCa4
Supplier: NSJ Bioreagents
Supplier-Nr: RQ7087

Properties

Application: WB, Direct ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant human protein (amino acids M1-A400)
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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