Anti-Kaiso

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A303-557A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A303-557A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Transcriptional regulator with bimodal DNA-binding specificity. Binds to... more

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Product information "Anti-Kaiso"

Protein function: Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. May contribute to the repression of target genes of the Wnt signaling pathway. May also activate transcription of a subset of target genes by the recruitment of CTNND2. Represses expression of MMP7 in conjunction with transcriptional corepressors CBFA2T3, CBFA2T2 and RUNX1T1 (PubMed:23251453). [The UniProt Consortium]

Keywords:	Anti-KAISO, Anti-ZBTB33, Anti-Transcriptional regulator Kaiso, Anti-Zinc finger and BTB domain-containing protein 33
Supplier:	Bethyl Laboratories
Supplier-Nr:	A303-557A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: dog, horse, panda, orangutan, rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, crab-eating macaque, european domestic ferret, naked mole rat, thirteen-lined ground squirrel, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A303-557A-T maps to a region between residue 375 and 425 of human Transcriptional regulator Kaiso using the numbering given in entry NP_006768.1 (GeneID 10009).
Format:	Antigen Affinity Purified