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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES2649.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES2649.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family... more
Product information "Anti-IRTKS"
This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal fo Protein function: May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.. Cellular localization: Cytoplasm, cytoskeleton . Recruited to actin pedestals that are formed upon infection by bacteria at bacterial attachment sites.
Keywords: | Anti-IRTKS, Anti-BAIAP2L1, Anti-BAI1-associated protein 2-like protein 1, Anti-Insulin receptor tyrosine kinase substrate, Anti-Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1, IRTKS rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES2649 |
Properties
Application: | WB, IHC, IF, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | The antiserum was produced against synthesized peptide derived from human BAIAP2L1. AA range:111-160 |
MW: | 57 kD |
Format: | Antiserum |
Database Information
KEGG ID : | K20127 | Matching products |
UniProt ID : | Q9UHR4 | Matching products |
Gene ID | GeneID 55971 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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