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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ELK-ES4513.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
| ELK-ES4513.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme... more
Product information "Anti-IREbeta"
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:The kinase domain is activated by trans-autophosphorylation. Kinase activity is required for activation of the endoribonuclease domain.,function:Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.,similarity:Contains 1 KEN domain.,similarity:Contains 1 protein kinase domain., Protein function: Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins. [The UniProt Consortium] Recommended dilutions: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.. Cellular localization: Endoplasmic reticulum membrane , Single-pass type I membrane protein .
| Keywords: | Anti-IRE1b, Anti-hIRE2p, Anti-Ire1-beta, EC=3.1.26.-, EC=2.7.11.1, Anti-Endoribonuclease, Anti-Inositol-requiring protein 2, Anti-Serine/threonine-protein kinase, Anti-Endoplasmic reticulum-to-nucleus signaling 2, IREbeta rabbit pAb |
| Supplier: | ELK Biotechnology |
| Supplier-Nr: | ES4513 |
Properties
| Application: | IHC, IF, ELISA |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human ERN2. AA range:841-890 |
| Format: | Antiserum |
Database Information
| KEGG ID : | K11715 | Matching products |
| UniProt ID : | Q76MJ5 | Matching products |
| Gene ID | GeneID 10595 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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