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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-12-1201-20 | 20 µg | - |
3 - 11 business days* |
373.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
It recognizes a protein of 66kDa-170kDa, identified as involucrin. In Western blotting of... more
Product information "Anti-Involucrin (Squamous Cell Terminal Differentiation Marker) Recombinant Rabbit Monoclonal Antibo"
It recognizes a protein of 66kDa-170kDa, identified as involucrin. In Western blotting of cultured human keratinocytes, this MAb reacts with a 120kDa protein. It stains the involucrin in a variety of sizes: 170kDa in MCF-7 cells, a doublet of ~115kDa and 150kDa in gorilla and owl monkey, 66kDa in dog, and a doublet of 105kDa in pig. Its epitope maps between codon 421-568 of human involucrin. Involucrin is expressed in a range of stratified squamous epithelia, including the cornea, which lacks a distinct cornified layer. In normal epidermis, it is first expressed in the upper spinous layers, and in keratinocyte cultures, all cells that have left the basal layer express it. Involucrin expression is altered in pathological conditions: in psoriasis and other benign epidermal hyperplasias, involucrin expression begins closer to the basal layer than normal, expression is abnormal in squamous cell carcinomas and premalignant lesions, and is reduced in severe dysplasias of the larynx and cervix. Protein function: Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia. [The UniProt Consortium]
Keywords: | Anti-IVL, Anti-Involucrin, Anti-Involucrin (Squamous Cell Terminal Differentiation Marker) Recombinant Rabbit Monoclonal Antibody (Clone:IVRN/2113R) |
Supplier: | Abeomics |
Supplier-Nr: | 12-1201-20 |
Properties
Application: | IHC |
Antibody Type: | Monoclonal |
Clone: | IVRN/2113R |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, gorilla, owl monkey, pig,, dog |
Immunogen: | Recombinant full-length human IVL protein |
Format: | Purified |
Database Information
UniProt ID : | P07476 | Matching products |
Gene ID | GeneID 3713 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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