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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
I8432-29D.100 | 100 tests | - | - |
3 - 19 business days* |
901.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The IL-10 receptor consists of two chains, a ligand binding IL-10 Ra (IL-10 R1) chain and a... more
Product information "Anti-Interleukin 10R, beta (IL-10 R-beta, Interleukin 10 Receptor beta, IL-10R2, CD210b, CRF2-4) (AP"
The IL-10 receptor consists of two chains, a ligand binding IL-10 Ra (IL-10 R1) chain and a signaling chain known as IL-10 Rb (IL-10 R2). The human IL-10 Rb chain is a 325aa protein with 69% homology to its mouse counterpart. Stimulation of cells by IL-10 activates both Jak1 and Tyk2 kinases. The IL-10 Rb chain is also a component of the recently identified IL-22 receptor. Both chains of the IL-10 R are expressed on lymphocytes, monocytes, and neutrophils, with the IL-10 Rb chain expressed at higher levels than the IL-10 Ra chain in most cases. IL-10 signaling can affect a variety of immune functions, including inhibition of pro-inflammatory cytokine synthesis and regulation of the growth and function of B cells and antigen-presenting cells. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 10ul to label 1x10e6 human peripheral blood monocytes, Optimal dilutions to be determined by the researcher. Hybridoma: myeloma cells with B cells Balb/c mice. Absorption: 620-650nm , Emission: 660-670nm, Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Keywords: | Anti-CRFB4, Anti-IL10RB, Anti-CDw210b, Anti-IL-10RB, Anti-IL-10R subunit 2, Anti-IL-10R subunit beta, Anti-IL-10 receptor subunit beta, Anti-Interleukin-10 receptor subunit 2, Anti-Cytokine receptor family 2 member 4 |
Supplier: | United States Biological |
Supplier-Nr: | I8432-29D |
Properties
Application: | FC |
Antibody Type: | Monoclonal |
Clone: | 11n101 |
Conjugate: | Alkaline Phosphatase |
Host: | Mouse |
Species reactivity: | mouse |
Immunogen: | Recombinant corresponding to aa20-220 from Interleukin 10 receptor beta expressed in NSO cells (Q08334). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K05135 | Matching products |
UniProt ID : | Q08334 | Matching products |
Gene ID | GeneID 3588 | Matching products |
Handling & Safety
Storage: | +4°C (do not freeze) |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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