Anti-Interleukin-1 Receptor Type I (IL-1RI)

Anti-Interleukin-1 Receptor Type I (IL-1RI)
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*1 Offer expires 31/03/2021
Item number Size Datasheet Manual SDS Delivery time Quantity Price
109-401-304 1 ml - -

3 - 9 business days*

1,427.00€
 
Protein function: Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates... more
Product information "Anti-Interleukin-1 Receptor Type I (IL-1RI)"
Protein function: Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. [The UniProt Consortium]
Keywords: Anti-IL1R, Anti-IL1R1
Supplier: Rockland Immunochemicals
Supplier-Nr: 109-401-304

Properties

Application: ELISA, RIA, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: recombinant human IL-1R type I
Format: Serum

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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