Anti-iNOS, clone K13-A

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG10574.50	50 µl		-	-	6 - 14 business days*		680.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Produces nitric oxide (NO) which is a messenger molecule with diverse functions... more

Close menu

Product information "Anti-iNOS, clone K13-A"

Protein function: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body (PubMed:7531687, PubMed:7544004). In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH on 'Cys-247' implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM (PubMed:25417112). Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8 (PubMed:19688109). [The UniProt Consortium]

Keywords:	Anti-iNOS, Anti-NOS2, Anti-NOS2A, Anti-HEP-NOS, Anti-NOS type II, Anti-Inducible NOS, EC=1.14.13.39, Anti-Hepatocyte NOS, Anti-Inducible NO synthase, Anti-Nitric oxide synthase, inducible, Anti-Peptidyl-cysteine S-nitrosylase NOS2
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG10574

Properties

Application:	WB
Antibody Type:	Monoclonal
Clone:	K13-A
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Synthetic peptide derived from Human iNOS
Format:	Antigen Affinity Purified