Anti-IL2RG / IL2 Receptor gamma

Anti-IL2RG / IL2 Receptor gamma
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-RQ5821 100 µg - -

3 - 10 business days*

755.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. IL2RG (INTERLEUKIN 2 RECEPTOR, GAMMA),also... more
Product information "Anti-IL2RG / IL2 Receptor gamma"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. IL2RG (INTERLEUKIN 2 RECEPTOR, GAMMA),also known as Common gamma chain or CD132, is a cytokine receptor sub-unit that is common to the receptor complexes for at least six different interleukin receptors:IL-2, IL-4, IL-7, IL-9, IL-15 and interleukin-21 receptor. IL2RG is a member of the type I cytokine receptor family expressed on most lymphocyte(white blood cell) populations, and its gene is found on the X-chromosome of mammals. By fluorescence in situ hybridization and PCR amplification of somatic cell hybrid DNAs, The IL2RG gene is mapped to Xq13.1. The IL2RG gene contains 8 exons and spans approximately 4.2 kb. And the gamma chain is an indispensable component of the functional IL2 receptor. Lymphocytes expressing the common gamma chain can form functional receptors for these cytokine proteins, which transmit signals from one cell to another and direct programs of cellular differentiation. The sharing of the gamma subunit by several receptors explains why humans and mice that lack IL2 entirely show milder symptoms than those with IL2RG deficiency. Protein function: Common subunit for the receptors for a variety of interleukins. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (PubMed:15123770). [The UniProt Consortium]
Keywords: Anti-p64, Anti-CD132, Anti-IL2RG, Anti-IL-2RG, Anti-gammaC, Anti-IL-2R subunit gamma, Anti-IL-2 receptor subunit gamma, Anti-Interleukin-2 receptor subunit gamma, Anti-Cytokine receptor common subunit gamma, IL2RG Antibody / IL2 Receptor gamma
Supplier: NSJ Bioreagents
Supplier-Nr: RQ5821

Properties

Application: WB, IF
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Amino acids QLQKKEIHLYQTFVVQLQD from the human protein
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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