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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V5184-20UG | 20 µg | - | - |
3 - 10 business days* |
332.00€
|
||
NSJ-V5184-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. IL-22RAlpha2... more
Product information "Anti-IL22RA2, clone IL22RA2/7291"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. IL-22RAlpha2 (Interleukin-22 receptor Alpha2 chain), also known as IL-22 binding protein (IL-22BP), cytokine receptor family class II member 10 (CRF2-10) or CRF2- soluble 1 (CRF2-S1), is a soluble, nonsignaling single chain receptor for IL-22. It is highly expressed in intestine and lymph nodes and is also found in spleen, kidney and liver. IL-22RAlpha2 has a cytokine-binding domain that contains two FnIII domains. Its affinity for IL-22 is 4- to 10-fold higher than that of the membrane-bound IL-22 receptor, however it has a dissociation rate up to 20 times lower. By binding to IL-22, IL-22RAlpha2 prevents the binding to the IL-22 membrane-bound receptor and therefore inhibits IL-22 signaling. This suggests that IL-22RAlpha2 may be important in regulating inflammatory responses. In addition, IL-22RAlpha2 can be induced by lipopolysaccharides (LPSs). Protein function: Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses. [The UniProt Consortium]
Keywords: | Anti-IL22BP, Anti-CRF2-S1, Anti-CRF2-10, Anti-IL22RA2, Anti-IL-22BP, Anti-IL-22RA2, Anti-ZcytoR16, Anti-IL-22R-alpha-2, Anti-IL-22 receptor subunit alpha-2, Anti-Interleukin-22-binding protein, Anti-Cytokine receptor class-II member 10, IL22RA2 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V5184 |
Properties
Application: | IHC (paraffin) |
Antibody Type: | Monoclonal |
Clone: | IL22RA2/7291 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | A recombinant partial protein sequence (within amino acids 1-200) from the human protein |
Format: | Purified |
Database Information
KEGG ID : | K05139 | Matching products |
UniProt ID : | Q969J5 | Matching products |
Gene ID | GeneID 116379 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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