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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V5186-20UG | 20 µg | - | - |
3 - 10 business days* |
332.00€
|
||
NSJ-V5186-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. The class II cytokine... more
Product information "Anti-IL20RA / IL-20 receptor subunit alpha, clone IL20RA/1752"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. The class II cytokine receptor family includes 12 members, 11 of which combine as various heterodimers to transduce signals across the cellular membrane for 27 cytokines. These cytokines are divided into four structurally related groups: six cytokines of the IL-10 family, 17 type I IFNs, one type II IFN and three IFN-l. IL-20 is a member of the IL-10 family of cytokines that has been shown to be upregulated in psoriatic skin. The receptor for IL-20 (IL-20R) exists as a dimer consisting of IL-20Ra and IL-20Rb. IL-20R also functions as a receptor for IL-19, IL-24 and IL-26. It is highly expressed in skin, brain and testis. IL-20, IL-20Ra and IL-20Rb all have higher expression levels in psoriatic lesional (LS) skin than in nonlesional (NL) skin, suggesting a role for these proteins as potential therapeutic targets. IL-20 can induce signal transducer and activator of transcription (Stat) activation through IL-20R. Protein function: The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26. [The UniProt Consortium]
Keywords: | Anti-CRF2-8, Anti-IL20RA, Anti-IL-20RA, Anti-IL-20R1, Anti-ZcytoR7, Anti-IL-20R-alpha, Anti-IL-20 receptor subunit alpha, Anti-Cytokine receptor family 2 member 8, Anti-Cytokine receptor class-II member 8, Anti-Interleukin-20 receptor subunit alpha, IL20R |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V5186 |
Properties
Application: | IHC (paraffin) |
Antibody Type: | Monoclonal |
Clone: | IL20RA/1752 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | A recombinant partial protein sequence (within amino acids 1-200) from the human protein |
Format: | Purified |
Database Information
KEGG ID : | K05136 | Matching products |
UniProt ID : | Q9UHF4 | Matching products |
Gene ID | GeneID 53832 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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