Anti-IL-6 (Sarilumab Biosimilar In Vivo Antibody (Fc Reduced))

Anti-IL-6 (Sarilumab Biosimilar In Vivo Antibody (Fc Reduced))
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-IVMB0220.500 500 µg - -

9 - 20 business days*

620.00€
 
Endotoxin level: < 1.0 EU/mg as determined by the LAL method. Protein function: Cytokine with a... more
Product information "Anti-IL-6 (Sarilumab Biosimilar In Vivo Antibody (Fc Reduced))"
Endotoxin level: < 1.0 EU/mg as determined by the LAL method. Protein function: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans- signaling'. Alternatively, 'cluster signaling' occurs when membrane- bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable). [The UniProt Consortium]
Keywords: Anti-CDF, Anti-IL-6, Anti-IFNB2, Anti-BSF-2, Anti-IFN-beta-2, Anti-Interleukin-6, Anti-Interferon beta-2, Anti-Hybridoma growth factor, Anti-CTL differentiation factor, Anti-B-cell stimulatory factor 2
Supplier: Assay Genie
Supplier-Nr: IVMB0220

Properties

Application: WB, ELISA, FA, FC, IHC, Neutr., WB
Antibody Type: Monoclonal
Clone: Hu137
Conjugate: No
Host: Human
Species reactivity: human
Purity: >95% monomer (analytical SEC)
Format: Functional Grade

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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