Anti-IKB alpha, clone 1121CT8.6.1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG55667.100	100 µl		-	-	6 - 14 business days*		584.00€

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Protein function: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL... more

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Product information "Anti-IKB alpha, clone 1121CT8.6.1"

Protein function: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. [The UniProt Consortium]

Keywords:	Anti-IKBA, Anti-NFKBIA, Anti-IkB-alpha, Anti-IkappaBalpha, Anti-I-kappa-B-alpha, Anti-NF-kappa-B inhibitor alpha, Anti-Major histocompatibility complex enhancer-binding protein MAD3
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG55667

Properties

Application:	WB
Antibody Type:	Monoclonal
Clone:	1121CT8.6.1
Conjugate:	No
Host:	Mouse
Species reactivity:	human, mouse
Immunogen:	Purified His-tagged Human IKB alpha
Format:	Purified