Anti-IkB- Alpha (Ab-32/36)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABE-35-1471-50	50 µl		-		3 - 11 business days*		574.00€

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Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm... more

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Product information "Anti-IkB- Alpha (Ab-32/36)"

Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to tranlocate to the nucleus and activate transcription. Protein function: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. [The UniProt Consortium]

Keywords:	Anti-IKBA, Anti-NFKBIA, Anti-IkB-alpha, Anti-IkappaBalpha, Anti-I-kappa-B-alpha, Anti-NF-kappa-B inhibitor alpha, Anti-Major histocompatibility complex enhancer-binding protein MAD3, Polyclonal Antibody to IkB- Alpha (Ab-32/36)
Supplier:	Abeomics
Supplier-Nr:	35-1471-50

Properties

Application:	IHC, WB, IF
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	mouse, human
Immunogen:	Peptide sequence around aa.30~34/34~38 (H-D-S-G-L- D-S -M-K) derived from Human IkB-a.
Format:	Purified