Anti-ICAM-1 (Ab-512)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABE-35-1458-100	100 µg		-		3 - 11 business days*		682.00€

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ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin a-L/beta-2). During... more

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Product information "Anti-ICAM-1 (Ab-512)"

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin a-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. Greenwood J, et al. (2003) J Immunol, 171(4):2099-2108. Zhou Z, et al. (2005) Eur J Pharmacol, 513(1-2):1-8. Chen YH, et al. (2001) J Cell Biochem, 82(3):512-521 Protein function: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans- endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. [The UniProt Consortium]

Keywords:	Anti-CD54, Anti-ICAM1, Anti-ICAM-1, Anti-Major group rhinovirus receptor, Anti-Intercellular adhesion molecule 1, Polyclonal Antibody to ICAM-1 (Ab-512)
Supplier:	Abeomics
Supplier-Nr:	35-1458

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Peptide sequence around aa. 510~514 (K-K-Y-R-L) derived from Human ICAM-1.
Format:	Purified