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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-AB-F1273UE.25 | 25 µg | - |
7 - 16 business days* |
69.00€
|
|||
E-AB-F1273UE.100 | 100 µg | - |
7 - 16 business days* |
226.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell... more
Product information "Anti-Human/Mouse KLRG-1, APC conjugated, clone 2F1"
Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag). KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3. It is composed of a homodimer of glycosylated 30-38 kD subunits. Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells. KLRG1 is also expressed on subsets of CD8+ and CD4+ cells, including CD4+ and CD8+ effector/memory cells, potent regulatory CD4+ T cells. KLRG1 may be involved in regulating NK cell homeostasis. KLRG22 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells. Protein function: Plays an inhibitory role on natural killer (NK) cells and T- cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E- cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells. [The UniProt Consortium]
Keywords: | Anti-KLRG1, Anti-CLEC15A, Anti-MAFA-like receptor, Anti-ITIM-containing receptor MAFA-L, Anti-Mast cell function-associated antigen, Anti-C-type lectin domain family 15 member A, Anti-Killer cell lectin-like receptor subfamily G member 1, APC Anti-Human/M |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-F1273UE |
Properties
Application: | FC, FC (membrane) |
Antibody Type: | Monoclonal |
Clone: | 2F1 |
Conjugate: | APC |
Host: | Syrian Hamster |
Species reactivity: | human, mouse |
Database Information
KEGG ID : | K10076 | Matching products |
UniProt ID : | Q96E93 | Matching products |
Gene ID | GeneID 10219 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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