Anti-Human CD95 (Clone: BR18 )

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABE-10-4136-25	25 µg		-		3 - 11 business days*		136.00€

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Protein function: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the... more

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Product information "Anti-Human CD95 (Clone: BR18 )"

Protein function: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death- inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS- mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). [The UniProt Consortium]

Keywords:	Anti-FAS, Anti-APT1, Anti-CD95, Anti-Apo-1 antigen, Anti-FASLG receptor, Anti-Apoptosis-mediating surface antigen FAS, Anti-Tumor necrosis factor receptor superfamily member 6, Monoclonal Antibody to Human CD95 (Clone: BR18 )
Supplier:	Abeomics
Supplier-Nr:	10-4136-25

Properties

Application:	FC
Antibody Type:	Monoclonal
Clone:	BR18
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	A partial length Recombinant protein of human CD95 was taken as immunogen for this antibody.
Format:	Purified