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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ABD-108510L0 | 100 tests | - |
3 - 8 business days* |
911.00€
|
|||
| ABD-108510L1 | 500 tests | - |
3 - 8 business days* |
3,414.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
iFluor 750 Protein function: Receptor for class I MHC antigens. Recognizes a broad spectrum of... more
Product information "Anti-human CD85j, clone GHI/75, iFluor(TM) 750"
iFluor 750 Protein function: Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles (PubMed:16455647, PubMed:28636952). Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. Engagement of LILRB1 present on natural killer cells or T-cells by class I MHC molecules protects the target cells from lysis. Interaction with HLA-B or HLA-E leads to inhibition of FCER1A signaling and serotonin release. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions (PubMed:11907092, PubMed:9285411, PubMed:9842885). Recognizes HLA-G in complex with B2M/beta-2 microglobulin and a nonamer self-peptide (PubMed:16455647). Upon interaction with peptide-bound HLA-G-B2M complex, triggers secretion of growth-promoting factors by decidual NK cells (PubMed:29262349, PubMed:19304799). Reprograms B cells toward an immune suppressive phenotype (PubMed:24453251). [The UniProt Consortium], iFluor(TM) 750 Anti-human CD85j Antibody *GHI/75*
| Keywords: | Anti-CD85j, Anti-LIR-1, Anti-MIR-7, Anti-ILT-2, Anti-Immunoglobulin-like transcript 2, Anti-CD85 antigen-like family member J, Anti-Leukocyte immunoglobulin-like receptor 1, Anti-Monocyte/macrophage immunoglobulin-like receptor 7, iFluor(TM) 750 Anti-huma |
| Supplier: | AAT Bioquest |
| Supplier-Nr: | 108510L |
Properties
| Application: | FC, IF |
| Antibody Type: | Monoclonal |
| Clone: | GHI/75 |
| Conjugate: | iFluor 750 |
| Host: | Mouse |
| Species reactivity: | human |
| Format: | Affinity Purified |
Database Information
| KEGG ID : | K06512 | Matching products |
| UniProt ID : | Q8NHL6 | Matching products |
| Gene ID | GeneID 10859 | Matching products |
Handling & Safety
| Storage: | +4°C (protect from light) |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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