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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-AB-F1162C.200 | 200 tests | - |
7 - 16 business days* |
404.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CD303, also known as BDCA-2 and CLEC4C, is a 38 kD type II transmembrane glycoprotein. It is a... more
Product information "Anti-Human CD303, FITC conjugated, clone 201A"
CD303, also known as BDCA-2 and CLEC4C, is a 38 kD type II transmembrane glycoprotein. It is a member of the C-type lectin superfamily. CD303 is expressed by plasmacytoid dendritic cells (pDCs) and is involved in cell adhesion, signaling, and antigen capture and processing. Crosslinking of CD303 inhibits the production of IFN-alpha/beta and TLR-9 induced pDCs maturation. Protein function: Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells (PubMed:11748283, PubMed:21880719, PubMed:25995448). Specifically recognizes non-sialylated galactose- terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man (PubMed:21880719, PubMed:25995448). Binds to serum IgG (PubMed:25995448). Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells (PubMed:11748283). May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells (PubMed:11748283, PubMed:21880719). May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium (PubMed:11748283). [The UniProt Consortium]
Keywords: | Anti-BDCA2, Anti-CD303, Anti-CLEC4C, Anti-BDCA-2, Anti-Dendritic lectin, Anti-Blood dendritic cell antigen 2, Anti-C-type lectin superfamily member 7, Anti-C-type lectin domain family 4 member C, FITC Anti-Human CD303 Antibody[201A] |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-F1162C |
Properties
Application: | FC, FC (membrane) |
Antibody Type: | Monoclonal |
Clone: | 201A |
Conjugate: | Fluorescein |
Host: | Mouse |
Species reactivity: | human |
Database Information
KEGG ID : | K06723 | Matching products |
UniProt ID : | Q8WTT0 | Matching products |
Gene ID | GeneID 170482 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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