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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-10-4105-25 | 25 µg | - |
3 - 11 business days* |
153.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
TSLPR (thymic stromal lymphopoietin receptor) also known as CRLF2 (cytokine receptor-like factor... more
Product information "Anti-hTSLPR (Clone: ABM3B96)"
TSLPR (thymic stromal lymphopoietin receptor) also known as CRLF2 (cytokine receptor-like factor 2) is a member of type I cytokine receptor. It binds its ligand TSLP (thymic stromal lymphopoietin) as a heterodimer with IL7R. TSLP ligand is produced by epithelial cells in order to activate dendritic cells, and is involved in inflammation, allergic responses as well as B-cell precursor proliferation and survival. The interaction between TSLP and its heterodimeric receptor activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. High expression of CRLF2 is associated with a poor prognosis in adult and high-risk pediatric cases of B-ALL (B-cell acute lymphoblastic leukemias). Protein function: Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2. Implicated in the development of the hematopoietic system. [The UniProt Consortium]
Keywords: | Anti-CRL2, Anti-CRLF2, Anti-IL-XR, Anti-TSLP receptor, Anti-Cytokine receptor-like 2, Anti-Cytokine receptor-like factor 2, Anti-Thymic stromal lymphopoietin protein receptor, Monoclonal Antibody to hTSLPR (Clone: ABM3B96) |
Supplier: | Abeomics |
Supplier-Nr: | 10-4105-25 |
Properties
Application: | WB |
Antibody Type: | Monoclonal |
Clone: | ABM3B96 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | A partial length recombinant TSLPR protein (amino acids 102-310) was used as the immunogen for this antibody. |
Format: | Purified |
Database Information
KEGG ID : | K05078 | Matching products |
UniProt ID : | Q9HC73 | Matching products |
Gene ID | GeneID 64109 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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