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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-R31738 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Heat shock protein 47, also known as... more
Product information "Anti-HSP47"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Heat shock protein 47, also known as SERPINH1, is a serpin which serves as a human chaperone protein for collagen. It is a member of the serpin superfamily of serine proteinase inhibitors. Its expression is induced by heat shock. HSP47 localizes to the endoplasmic reticulum lumen and binds collagen, thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to this protein have been found in patients with rheumatoid arthritis. It has been found that HSP47 monitors the integrity of the triple helix of type I procollagen at the ER/cis-Golgi boundary and, when absent, the rate of transit from the ER to the Golgi is increased and the helical structure is compromised. Protein function: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen. [The UniProt Consortium]
Keywords: | Anti-CBP1, Anti-AsTP3, Anti-PIG14, Anti-SERPINH1, Anti-Colligin, Anti-Serpin H1, Anti-Collagen-binding protein, Anti-47 kDa heat shock protein, Anti-Arsenic-transactivated protein 3, Anti-Rheumatoid arthritis-related antigen RA-A47, HSP47 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | R31738 |
Properties
Application: | WB, IHC (paraffin) |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Human partial recombinant protein (AA 247-418) |
Format: | Purified |
Database Information
KEGG ID : | K09501 | Matching products |
UniProt ID : | P50454 | Matching products |
Gene ID | GeneID 871 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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