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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
H1830-53L-PE.200 | 200 µl | - | - |
3 - 19 business days* |
993.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
In response to adverse changes in their environment, cells from many organisms increase the... more
Product information "Anti-HSP27 (S83) (Heat Shock Protein beta-1, HspB1, Heat Shock 27kD Protein, HSP 27, Stress-responsi"
In response to adverse changes in their environment, cells from many organisms increase the expression of a class of proteins referred to as heat shock or stress proteins. HSBP1 exhibits rapid increased phosphorylation in response to various mitogens, tumor promoters (e.g. phorbol esters) and calcium ionophores, and high levels are associated with carcinoma of the breast and with endometrial adenocarcinomas. Heat shock of HeLa cell cultures, or treatment with arsenite, phorbol ester, or tumor necrosis factor, causes a rapid phosphorylation of preexisting HSBP1, with Ser82 as the major site and Ser78 the minor site of phosphorylation. HSBP1 may exert phosphorylation-activated functions linked with growth signaling pathways in unstressed cells. A homeostatic function at this level could protect cells from adverse effects of signal transduction systems which may be activated inappropriately during stress. Applications: Suitable for use in FLISA and Western Blot. Other applications not tested. Recommended Dilution: FLISA: 1:1,000, Western Blot: 1:50-1:100, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months after receipt at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light., , Note: Applications are based on unconjugated antibody.
Keywords: | Anti-SRP27, Anti-HSP27, Anti-HSPB1, Anti-HspB1, Anti-HSP 27, Anti-Heat shock protein beta-1, Anti-Heat shock 27 kDa protein, Anti-28 kDa heat shock protein, Anti-Stress-responsive protein 27, Anti-Estrogen-regulated 24 kDa protein |
Supplier: | United States Biological |
Supplier-Nr: | H1830-53L-PE |
Properties
Application: | FLISA, WB |
Antibody Type: | Polyclonal |
Conjugate: | Phycoerythrin |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Synthetic non-phosphopeptide corresponding to amino acid residues surrounding S83 of human HSPB1 (KLH). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K04455 | Matching products |
UniProt ID : | P04792 | Matching products |
Gene ID | GeneID 3315 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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