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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES5787.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES5787.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The protein encoded by this gene is induced by environmental stress and developmental changes.... more
Product information "Anti-HSP27"
The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN). [provided by RefSeq, Oct 2008], Protein function: Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state (PubMed:10383393, PubMed:20178975). Plays a role in stress resistance and actin organization (PubMed:19166925). Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins (PubMed:23728742). [The UniProt Consortium] Recommended dilutions: IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.. Cellular localization: Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, spindle . Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles. .
Keywords: | Anti-HspB1, Anti-HSPB1, Anti-SRP27, Anti-HSP27, Anti-HSP 27, Anti-Heat shock 27 kDa protein, Anti-Heat shock protein beta-1, Anti-28 kDa heat shock protein, Anti-Stress-responsive protein 27, Anti-Estrogen-regulated 24 kDa protein, HSP27 rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES5787 |
Properties
Application: | IF, WB, IHC, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | The antiserum was produced against synthesized peptide derived from human HSP27. AA range:48-97 |
MW: | 27 kD |
Format: | Antiserum |
Database Information
KEGG ID : | K04455 | Matching products |
UniProt ID : | P04792 | Matching products |
Gene ID | GeneID 3315 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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