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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
H7520-02.100 | 100 µg | - | - |
3 - 19 business days* |
947.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
HS6ST3 (Heparin sulfate 6-O-sulfotransferase 3) is a 60-62kD member of the sulfotransferase 6... more
Product information "Anti-HS6ST3 (Heparan sulfate 6-O-sulfotransferase 3)"
HS6ST3 (Heparin sulfate 6-O-sulfotransferase 3) is a 60-62kD member of the sulfotransferase 6 family of enzymes. It is one of three 6-O sulfotransferase isoforms, all of which essentially perform the same function, but all of which are the products of distinct genes. HS6ST3 is known to sulfate the #6 position of glucosamine sulfate that is linked to a 2-O-sulfated iduronic acid in heparin sulfate. The molecule shows a temporal expression pattern, being found in postnatal cerebellar Purkinje cells and cerebral cortical pyramidal cells in layers II/III and V. Mouse HS6ST3 is a 470aa type II transmembrane glycoprotein. It contains a short four aa cytoplasmic N-terminus coupled to an extended 443aa lumenal domain (aa28-470). The lumenal domain contains a stem region (aa28-83) that mediates oligomerization and Golgi localization, plus a sulfotransferase enzyme domain (aa142-409). Cleavage within the stem region by b-secretase generates a soluble form of HS6ST3. Over aa28-470, mouse HS6ST3 shares 99-95aa identity with rat and human HS6ST3, respectively. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry: 5-15ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | EC=2.8.2.-, Anti-HS6ST-3, Anti-mHS6ST-3, Anti-Heparan-sulfate 6-O-sulfotransferase 3 |
Supplier: | United States Biological |
Supplier-Nr: | H7520-02 |
Properties
Application: | IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Sheep |
Species reactivity: | mouse |
Immunogen: | Recombinant corresponding to aa28-470 from mouse HS6ST3 expressed in CHO cells (NP_056635). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K08103 | Matching products |
UniProt ID : | Q9QYK4 | Matching products |
Gene ID | GeneID 50787 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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