Anti-HOPX

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA030180.25	25 µl		-		7 - 10 business days*		300.00€
ATA-HPA030180.100	100 µl		-		7 - 10 business days*		421.00€

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Protein function: Atypical homeodomain protein which does not bind DNA and is required to... more

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Product information "Anti-HOPX"

Protein function: Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF- dependent cardiac-specific genes and cardiac development. Prevents SRF- dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy. May act as a tumor suppressor. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein refolding (PubMed:27708256). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 74% and to rat: 74%

Keywords:	Anti-HOD, Anti-HOPX, Anti-Odd homeobox protein 1, Anti-Homeodomain-only protein, Anti-Lung cancer-associated Y protein, Anti-Not expressed in choriocarcinoma protein 1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA030180

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: MLIFLGCYRR RLEERAGTMS AETASGPTED QVEILEYNFN KVDKHPDSTT LCLIAAEAGL SEEETQKWFK QRLAKWRRSE GLPSECRSVT D (ATA-APrEST78383)