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Discount Promotion
Promotion:
Get 15% Discount on Antibodies and Biosimilars by Abeomics!
*1
*1 Offer expires 30/06/2024
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Discount | Price |
---|---|---|---|---|---|---|---|---|
ABE-11-7017-100 | 100 µg | - |
3 - 11 business days* |
15 %
|
387.00€
328.95€ |
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Histone H2A is one of the five main histone proteins that is approximately 14 kDa protein... more
Product information "Anti-Histone H2A"
Histone H2A is one of the five main histone proteins that is approximately 14 kDa protein consisting of 130 amino acid residues and present in the nucleosome in the form of H2A-H2B heterodimer. H2A is mainly composed of non-allelic variants and interestingly atypical variants, such as, MacroH2As, H2A.X, H2A-Bbd, differ considerably in size with H2A. H2A undergoes various post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination, which occur in response to various stimuli and directly affect the accessibility of chromatin to transcription factors. This gene is mainly expressed on blood, brain, breast and it plays a significant role in the disease, riddle syndrome. Protein function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [The UniProt Consortium]
Keywords: | Anti-H2AFM, Anti-H2AFA, Anti-HIST1H2AE, Anti-HIST1H2AB, Anti-Histone H2A.2, Anti-Histone H2A/m, Anti-Histone H2A/a, Anti-Histone H2A type 1-B/E, Polyclonal Antibody to Histone H2A |
Supplier: | Abeomics |
Supplier-Nr: | 11-7017 |
Properties
Application: | IHC, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Full length recombinant Histone H2A protein was used as the immunogen for this antibody. |
Format: | Purified |
Database Information
KEGG ID : | K11251 | Matching products |
UniProt ID : | P04908 | Matching products |
Gene ID | GeneID 3012 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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