Anti-HIPK3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG54855.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Serine/threonine-protein kinase involved in transcription regulation, apoptosis... more

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Product information "Anti-HIPK3"

Protein function: Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF- responsive element (OCFRE). [The UniProt Consortium]

Keywords:	Anti-ANPK, Anti-FIST, Anti-DYRK6, Anti-HIPK3, EC=2.7.11.1, Anti-Homolog of protein kinase YAK1, Anti-Homeodomain-interacting protein kinase 3, Anti-Fas-interacting serine/threonine-protein kinase, Anti-Androgen receptor-interacting nuclear protein kinase
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG54855

Properties

Application:	IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse, rat)
Immunogen:	KLH-conjugated synthetic peptide corresponding to aa. 1127-1156 (C-terminus) of Human HIPK3
Format:	Purified